8HD8
Crystal structure of TMPRSS2 in complex with 212-148
Summary for 8HD8
Entry DOI | 10.2210/pdb8hd8/pdb |
Descriptor | Transmembrane protease serine 2 catalytic chain, CALCIUM ION, 4-carbamimidamidobenzoic acid, ... (6 entities in total) |
Functional Keywords | inhibitor, complex, host, antiviral, antiviral protein, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 88482.52 |
Authors | |
Primary citation | Wang, H.,Yang, Q.,Liu, X.,Xu, Z.,Shao, M.,Li, D.,Duan, Y.,Tang, J.,Yu, X.,Zhang, Y.,Hao, A.,Wang, Y.,Chen, J.,Zhu, C.,Guddat, L.,Chen, H.,Zhang, L.,Chen, X.,Jiang, B.,Sun, L.,Rao, Z.,Yang, H. Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14:7574-7574, 2023 Cited by PubMed: 37990007DOI: 10.1038/s41467-023-42527-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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