8HBE

Structure of human soluble guanylate cyclase in the inactive state at 3.1 angstrom

Summary for 8HBE

• Entry DOI: 10.2210/pdb8hbe/pdb
• EMDB information: 34623
• Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: soluble guanylate cyclase, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 148782.29

Authors

Chen, L.,Liu, R. (deposition date: 2022-10-28, release date: 2023-04-19, Last modification date: 2024-07-03)

• Primary citation: Liu, R.,Kang, Y.,Chen, L.; NO binds to the distal site of haem in the fully activated soluble guanylate cyclase.; Nitric Oxide, 134-135:17-22, 2023; PubMed: 36972843; DOI: 10.1016/j.niox.2023.03.002

Experimental method

ELECTRON MICROSCOPY (3.2 Å)