8H59
A fungal MAP kinase in complex with an inhibitor
Summary for 8H59
Entry DOI | 10.2210/pdb8h59/pdb |
Descriptor | Mitogen-activated protein kinase MPS1, ~{N}-[(2~{S})-3-(1~{H}-indol-3-yl)-1-(methylamino)-1-oxidanylidene-propan-2-yl]-8-[2-methoxy-5-(trifluoromethyloxy)phenyl]-1,6-naphthyridine-2-carboxamide (3 entities in total) |
Functional Keywords | kinase, fungal, signaling protein-inhibitor complex, signaling protein/inhibitor |
Biological source | Pyricularia oryzae 70-15 |
Total number of polymer chains | 1 |
Total formula weight | 46721.88 |
Authors | |
Primary citation | Kong, Z.,Zhang, X.,Zhou, F.,Tang, L.,Chen, Y.,Li, S.,Zhang, X.,Kuai, L.,Su, W.,Cui, W.,Cai, J.,Wang, Y.,Yang, J.,Peng, Y.L.,Wang, D.,Liu, J. Structure-Aided Identification of an Inhibitor Targets Mps1 for the Management of Plant-Pathogenic Fungi. Mbio, 14:e0288322-e0288322, 2023 Cited by PubMed: 36779710DOI: 10.1128/mbio.02883-22 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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