8H0N

Crystal structure of the human METTL1-WDR4 complex

Summary for 8H0N

• Entry DOI: 10.2210/pdb8h0n/pdb
• Descriptor: tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA (guanine-N(7)-)-methyltransferase (3 entities in total)
• Functional Keywords: transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 68578.87

Authors

Jin, X.H.,Guan, Z.Y.,Gong, Z.,Zhang, D.L. (deposition date: 2022-09-30, release date: 2023-07-05, Last modification date: 2023-11-08)

• Primary citation: Jin, X.,Guan, Z.,Hu, N.,He, C.,Yin, P.,Gong, Z.,Zhang, D.; Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1.; Cell Discov, 9:65-65, 2023; PubMed: 37369656; DOI: 10.1038/s41421-023-00562-y

Experimental method

X-RAY DIFFRACTION (1.8 Å)