8H0N
Crystal structure of the human METTL1-WDR4 complex
Summary for 8H0N
Entry DOI | 10.2210/pdb8h0n/pdb |
Descriptor | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA (guanine-N(7)-)-methyltransferase (3 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 68578.87 |
Authors | Jin, X.H.,Guan, Z.Y.,Gong, Z.,Zhang, D.L. (deposition date: 2022-09-30, release date: 2023-07-05, Last modification date: 2023-11-08) |
Primary citation | Jin, X.,Guan, Z.,Hu, N.,He, C.,Yin, P.,Gong, Z.,Zhang, D. Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1. Cell Discov, 9:65-65, 2023 Cited by PubMed: 37369656DOI: 10.1038/s41421-023-00562-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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