8GZB

SARS-CoV-2 3CLpro

Summary for 8GZB

Entry DOI	10.2210/pdb8gzb/pdb
Descriptor	3C-like proteinase nsp5, 1,2-ETHANEDIOL, 2-(4-chlorophenyl)-1,3,4-oxadiazole, ... (4 entities in total)
Functional Keywords	inhibitor, complex, recombination, viral protein, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2)
Total number of polymer chains	1
Total formula weight	34068.21
Authors	Wang, F.,Cen, Y.X.,Tian, P. (deposition date: 2022-09-26, release date: 2023-09-27, Last modification date: 2024-04-10)
Primary citation	Li, Q.H.,Zhang, G.S.,Wang, F.,Cen, Y.,Liu, X.L.,Zhang, J.W.,Wang, Y.H.,Lee, A.W.M.,Gao, D.,Lin, G.Q.,Tian, P. Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation. Sci Adv, 9:eadg1237-eadg1237, 2023 Cited by PubMed: 37163601 DOI: 10.1126/sciadv.adg1237 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation