8GYB

Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-homocysteine

8GYB の概要

• エントリーDOI: 10.2210/pdb8gyb/pdb
• 分子名称: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• 機能のキーワード: methyltransferase, viral protein
• 由来する生物種: Alongshan virus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 128959.52

構造登録者

Chen, H.,Lin, S.,Lu, G.W. (登録日: 2022-09-22, 公開日: 2023-09-27, 最終更新日: 2024-04-10)

• 主引用文献: Chen, H.,Lin, S.,Yang, F.,Chen, Z.,Guo, L.,Yang, J.,Lin, X.,Wang, L.,Duan, Y.,Wen, A.,Zhang, X.,Dai, Y.,Yin, K.,Yuan, X.,Yu, C.,He, Y.,He, B.,Cao, Y.,Dong, H.,Li, J.,Zhao, Q.,Liu, Q.,Lu, G.; Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.; Plos Pathog., 19:e1011694-e1011694, 2023; PubMed: 37831643; DOI: 10.1371/journal.ppat.1011694

実験手法

X-RAY DIFFRACTION (2.101 Å)