8GV4

A human broadly neutralizing influenza A hemagglutinin stem-specific antibody PN-SIA28

Summary for 8GV4

• Entry DOI: 10.2210/pdb8gv4/pdb
• Descriptor: PN-SIA28 heavy chain, PN-SIA28 light chain (3 entities in total)
• Functional Keywords: influenza, hemagglutinin, antibody, broadly neutralizing, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 96894.39

Authors

Chen, Y.,Song, H.,Qi, J.,Gao, G.F. (deposition date: 2022-09-14, release date: 2022-12-21, Last modification date: 2023-11-08)

• Primary citation: Chen, Y.,Wang, F.,Yin, L.,Jiang, H.,Lu, X.,Bi, Y.,Zhang, W.,Shi, Y.,Burioni, R.,Tong, Z.,Song, H.,Qi, J.,Gao, G.F.; Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.; Nat Commun, 13:7603-7603, 2022; PubMed: 36494358; DOI: 10.1038/s41467-022-35236-y

Experimental method

X-RAY DIFFRACTION (2.5 Å)