8GQW

The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus

8GQW の概要

• エントリーDOI: 10.2210/pdb8gqw/pdb
• 分子名称: MHC class I antigen, beta 2 microglobulin, Hu64, ... (4 entities in total)
• 機能のキーワード: sla-2; foot-and-mouth disease virus; crystal; peptide; epitope; ctl; complex; peptide presentation; universal vaccine candidate, immune system, immune system-epitope complex, immune system/epitope
• 由来する生物種: Sus scrofa (pig); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 88500.35

構造登録者

Feng, L.,Gao, Y.Y.,Sun, M.W.,Li, Z.B.,Zhang, Q.,Yang, J.,Qiao, C.,Jin, H.,Feng, H.S.,Xian, Y.H.,Qi, J.X.,Gao, G.F.,Liu, W.J.,Gao, F.S. (登録日: 2022-08-31, 公開日: 2023-01-11, 最終更新日: 2023-10-25)

• 主引用文献: Feng, L.,Gao, Y.Y.,Sun, M.,Li, Z.B.,Zhang, Q.,Yang, J.,Qiao, C.,Jin, H.,Feng, H.S.,Xian, Y.H.,Qi, J.,Gao, G.F.,Liu, W.J.,Gao, F.S.; The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.; Cells, 11:-, 2022; PubMed: 36552780; DOI: 10.3390/cells11244017

実験手法

X-RAY DIFFRACTION (2.48 Å)