8GOC
Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R
Summary for 8GOC
Entry DOI | 10.2210/pdb8goc/pdb |
EMDB information | 34175 |
Descriptor | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... (4 entities in total) |
Functional Keywords | gpcr, arrestin, signaling protein, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 12 |
Total formula weight | 299867.90 |
Authors | Maharana, J.,Sarma, P.,Yadav, M.K.,Banerjee, R.,Shukla, A.K. (deposition date: 2022-08-24, release date: 2023-05-17, Last modification date: 2024-07-17) |
Primary citation | Maharana, J.,Sarma, P.,Yadav, M.K.,Saha, S.,Singh, V.,Saha, S.,Chami, M.,Banerjee, R.,Shukla, A.K. Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83:2091-2107.e7, 2023 Cited by PubMed: 37209686DOI: 10.1016/j.molcel.2023.04.025 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.18 Å) |
Structure validation
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