8GKC
Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640 - C2 refinement
Summary for 8GKC
Entry DOI | 10.2210/pdb8gkc/pdb |
EMDB information | 40182 |
Descriptor | Fatty acid synthase, denifanstat, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | fatty acid synthase, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 369358.82 |
Authors | Hasan, S.M.N.,Keszei, A.,Mazhab-Jafari, M.T. (deposition date: 2023-03-17, release date: 2023-05-24, Last modification date: 2024-06-19) |
Primary citation | Hasan, S.M.N.,Lou, J.W.,Keszei, A.F.A.,Dai, D.L.,Mazhab-Jafari, M.T. Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat. Nat Commun, 14:3460-3460, 2023 Cited by PubMed: 37308485DOI: 10.1038/s41467-023-39266-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.45 Å) |
Structure validation
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