8GB7

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 20A7

Summary for 8GB7

• Entry DOI: 10.2210/pdb8gb7/pdb
• Descriptor: 20A7 Heavy chain, 20A7 Light chain, Spike protein S1, ... (5 entities in total)
• Functional Keywords: covid-19, sars-cov-2, antibody, spike, receptor binding domain, immune system
• Biological source: Macaca mulatta (Rhesus monkey); More
• Total number of polymer chains: 3
• Total formula weight: 70562.64

Authors

Yuan, M.,Wilson, I.A. (deposition date: 2023-02-24, release date: 2023-05-24)

• Primary citation: Feng, Y.,Yuan, M.,Powers, J.M.,Hu, M.,Munt, J.E.,Arunachalam, P.S.,Leist, S.R.,Bellusci, L.,Kim, J.,Sprouse, K.R.,Adams, L.E.,Sundaramurthy, S.,Zhu, X.,Shirreff, L.M.,Mallory, M.L.,Scobey, T.D.,Moreno, A.,O'Hagan, D.T.,Kleanthous, H.,Villinger, F.J.,Veesler, D.,King, N.P.,Suthar, M.S.,Khurana, S.,Baric, R.S.,Wilson, I.A.,Pulendran, B.; Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.; Sci Transl Med, 15:eadg7404-eadg7404, 2023; PubMed: 37163615; DOI: 10.1126/scitranslmed.adg7404

Experimental method

X-RAY DIFFRACTION (2.57 Å)