8G93

Crystal structures of 17-beta-hydroxysteroid dehydrogenase 13

Summary for 8G93

Entry DOI	10.2210/pdb8g93/pdb
Related	8G84 8G89
Descriptor	Hydroxysteroid 17-beta dehydrogenase 13, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-fluoro-N-({(1r,4r)-4-[(2-fluorophenoxy)methyl]-1-hydroxycyclohexyl}methyl)-4-hydroxybenzamide, ... (4 entities in total)
Functional Keywords	17 beta-hydroxysteroid dehydrogenase 13; lipid droplet associated protein; inhibitor, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological source	Canis lupus familiaris (dog)
Total number of polymer chains	2
Total formula weight	72809.95
Authors	Liu, S. (deposition date: 2023-02-21, release date: 2023-08-09, Last modification date: 2023-09-06)
Primary citation	Liu, S.,Sommese, R.F.,Nedoma, N.L.,Stevens, L.M.,Dutra, J.K.,Zhang, L.,Edmonds, D.J.,Wang, Y.,Garnsey, M.,Clasquin, M.F. Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun, 14:5158-5158, 2023 Cited by PubMed: 37620305 DOI: 10.1038/s41467-023-40766-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation