8G25

Crystal Structure of Cathepsin-G and Neutrophil Elastase Inhibited by S. aureus EapH2 at pH 7.5

8G25 の概要

• エントリーDOI: 10.2210/pdb8g25/pdb
• 分子名称: Cathepsin-G, Neutrophil elastase, MAP domain-containing protein, ... (4 entities in total)
• 機能のキーワード: protease inhibitor, immune evasion, neutrophil, s. aureus, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Staphylococcus aureus subsp. aureus Mu50; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 185520.08

構造登録者

Mishra, N.B.,Geisbrecht, B.V. (登録日: 2023-02-03, 公開日: 2023-04-26, 最終更新日: 2023-10-25)

• 主引用文献: Mishra, N.,Herdendorf, T.J.,Prakash, O.,Geisbrecht, B.V.; Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2.; J.Biol.Chem., 299:104878-104878, 2023; PubMed: 37269950; DOI: 10.1016/j.jbc.2023.104878

実験手法

X-RAY DIFFRACTION (1.8 Å)