8G0G

Crystal structure of diphtheria toxin H223Q/H257Q double mutant (pH 4.5)

8G0G の概要

• エントリーDOI: 10.2210/pdb8g0g/pdb
• 分子名称: Diphtheria toxin, ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: diptheria toxin, ph dependent conformational changes, toxin
• 由来する生物種: Corynebacterium diphtheriae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 118756.37

構造登録者

Lovell, S.,Kashipathy, M.M.,Battaile, K.P.,Ladokhin, A.S. (登録日: 2023-01-31, 公開日: 2023-07-05, 最終更新日: 2023-08-09)

• 主引用文献: Rodnin, M.V.,Vasques-Montes, V.,Kyrychenko, A.,Oliveira, N.F.B.,Kashipathy, M.M.,Battaile, K.P.,Douglas, J.,Lovell, S.,Machuqueiro, M.,Ladokhin, A.S.; Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain.; Toxins, 15:-, 2023; PubMed: 37505680; DOI: 10.3390/toxins15070410

実験手法

X-RAY DIFFRACTION (2.1 Å)