8FVW

CryoEM structure of E.coli transcription elongation complex bound to ppGpp

Summary for 8FVW

• Entry DOI: 10.2210/pdb8fvw/pdb
• Related: 8FVW
• EMDB information: 29491 29494
• Descriptor: DNA-directed RNA polymerase subunit alpha, MAGNESIUM ION, SODIUM ION, ... (12 entities in total)
• Functional Keywords: transcription elongation, second messager, ppgpp, dna repair, transcription-dna-rna complex, transcription/dna/rna
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 8
• Total formula weight: 429203.35

Authors

Duan, W.,Serganov, A. (deposition date: 2023-01-19, release date: 2023-04-05, Last modification date: 2024-06-19)

• Primary citation: Weaver, J.W.,Proshkin, S.,Duan, W.,Epshtein, V.,Gowder, M.,Bharati, B.K.,Afanaseva, E.,Mironov, A.,Serganov, A.,Nudler, E.; Control of transcription elongation and DNA repair by alarmone ppGpp.; Nat.Struct.Mol.Biol., 30:600-607, 2023; PubMed: 36997761; DOI: 10.1038/s41594-023-00948-2

Experimental method

ELECTRON MICROSCOPY (2.1 Å)