Summary for 8FV7
Entry DOI | 10.2210/pdb8fv7/pdb |
Descriptor | CTP synthase, ADENOSINE-5'-TRIPHOSPHATE, SODIUM ION, ... (5 entities in total) |
Functional Keywords | inhibitor complex, metabolic enzyme, cytosolic protein, ligase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 123006.56 |
Authors | Holyoak, T.,McLeod, M.J.,Tran, N. (deposition date: 2023-01-18, release date: 2023-05-24, Last modification date: 2023-10-25) |
Primary citation | McLeod, M.J.,Tran, N.,McCluskey, G.D.,Gillis, T.D.,Bearne, S.L.,Holyoak, T. A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32:e4648-e4648, 2023 Cited by PubMed: 37106216DOI: 10.1002/pro.4648 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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