8FTJ
Crystal structure of human NEIL1 (P2G (242K) C(delta)100) glycosylase bound to DNA duplex containing urea
Summary for 8FTJ
Entry DOI | 10.2210/pdb8ftj/pdb |
Descriptor | Endonuclease 8-like 1, DNA (5'-D(*CP*GP*TP*CP*CP*AP*UDV*GP*TP*CP*TP*AP*CP)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*AP*TP*GP*GP*AP*CP*GP*G)-3'), ... (6 entities in total) |
Functional Keywords | base-excision repair enzyme, dna glycosylase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 41994.96 |
Authors | Tomar, R.,Sharma, P.,Harp, J.M.,Egli, M.,Stone, M.P. (deposition date: 2023-01-12, release date: 2023-04-26, Last modification date: 2024-05-01) |
Primary citation | Tomar, R.,Minko, I.G.,Sharma, P.,Kellum, A.H.,Lei, L.,Harp, J.M.,Iverson, T.M.,Lloyd, R.S.,Egli, M.,Stone, M.P. Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase. Nucleic Acids Res., 51:3754-3769, 2023 Cited by PubMed: 37014002DOI: 10.1093/nar/gkad164 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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