8FTB

Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation

Summary for 8FTB

• Entry DOI: 10.2210/pdb8ftb/pdb
• Descriptor: Integrin beta-2,Talin-1 (2 entities in total)
• Functional Keywords: integrin, beta-2, talin, ferm, complex, k306q, cell adhesion
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 1
• Total formula weight: 47405.41

Authors

Wu, J.,Gao, T. (deposition date: 2023-01-11, release date: 2024-07-03)

• Primary citation: Gao, T.,Kabir, S.,Wu, J.; Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation; Biorxiv, 2024; DOI: 10.1101/2024.05.28.596271

Experimental method

X-RAY DIFFRACTION (1.97 Å)