8FSZ
Full-length mouse 5-HT3A receptor in complex with ALB148471, open-like
Summary for 8FSZ
| Entry DOI | 10.2210/pdb8fsz/pdb |
| EMDB information | 29409 29411 29418 29422 |
| Descriptor | 5-hydroxytryptamine receptor 3A, 5-[(1R,3S,5R)-1-azabicyclo[3.2.2]nonan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | partial agonist, cys-loop, plgic, ion channel, transport protein |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 5 |
| Total formula weight | 316619.15 |
| Authors | Felt, K.C.,Chakrapani, S. (deposition date: 2023-01-11, release date: 2023-12-27, Last modification date: 2024-05-01) |
| Primary citation | Felt, K.,Stauffer, M.,Salas-Estrada, L.,Guzzo, P.R.,Xie, D.,Huang, J.,Filizola, M.,Chakrapani, S. Structural basis for partial agonism in 5-HT 3A receptors. Nat.Struct.Mol.Biol., 31:598-609, 2024 Cited by PubMed: 38177669DOI: 10.1038/s41594-023-01140-2 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.79 Å) |
Structure validation
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