8FSL
Human Mesothelin bound to a neutralizing VH domain antibody
Summary for 8FSL
Entry DOI | 10.2210/pdb8fsl/pdb |
Descriptor | VH domain, Mesothelin (2 entities in total) |
Functional Keywords | mesothelin vh, antitumor protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 6 |
Total formula weight | 115563.07 |
Authors | |
Primary citation | Sun, Z.,Chu, X.,Adams, C.,Ilina, T.V.,Guerrero, M.,Lin, G.,Chen, C.,Jelev, D.,Ishima, R.,Li, W.,Mellors, J.W.,Calero, G.,Dimitrov, D.S. Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate. Mol Ther Oncolytics, 31:100726-100726, 2023 Cited by PubMed: 37771390DOI: 10.1016/j.omto.2023.09.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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