8FPW
Crystal structure of tumor related RhoA mutant A161V in complex with GDP
Summary for 8FPW
Entry DOI | 10.2210/pdb8fpw/pdb |
Descriptor | Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | small g proteins, gtpase, fast-cycling mutant, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 21250.29 |
Authors | |
Primary citation | Lin, Y.,Ramelot, T.A.,Senyuz, S.,Gursoy, A.,Jang, H.,Nussinov, R.,Keskin, O.,Zheng, Y. Tumor-derived RHOA mutants interact with effectors in the GDP-bound state. Nat Commun, 15:7176-7176, 2024 Cited by PubMed: 39169042DOI: 10.1038/s41467-024-51445-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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