8FNY
Nucleotide-bound structure of a functional construct of eukaryotic elongation factor 2 kinase.
Summary for 8FNY
| Entry DOI | 10.2210/pdb8fny/pdb |
| Descriptor | Eukaryotic elongation factor 2 kinase, Calmodulin-1, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total) |
| Functional Keywords | elongation factor 2 kinase, eef2, eef2k, eef-2k, calmodulin, translation, atp, adp, allostery, translation-transferase complex, translation/transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 156364.05 |
| Authors | Piserchio, A.,Isiorho, E.A.,Dalby, K.N.,Ghose, R. (deposition date: 2022-12-28, release date: 2023-05-03) |
| Primary citation | Piserchio, A.,Long, K.J.,Browning, L.S.,Bohanon, A.L.,Isiorho, E.A.,Dalby, K.N.,Ghose, R. ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin. Proc.Natl.Acad.Sci.USA, 120:e2300902120-e2300902120, 2023 Cited by PubMed: 37068230DOI: 10.1073/pnas.2300902120 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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