8FNY

Nucleotide-bound structure of a functional construct of eukaryotic elongation factor 2 kinase.

8FNY の概要

• エントリーDOI: 10.2210/pdb8fny/pdb
• 分子名称: Eukaryotic elongation factor 2 kinase, Calmodulin-1, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: elongation factor 2 kinase, eef2, eef2k, eef-2k, calmodulin, translation, atp, adp, allostery, translation-transferase complex, translation/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 156364.05

構造登録者

Piserchio, A.,Isiorho, E.A.,Dalby, K.N.,Ghose, R. (登録日: 2022-12-28, 公開日: 2023-05-03)

• 主引用文献: Piserchio, A.,Long, K.J.,Browning, L.S.,Bohanon, A.L.,Isiorho, E.A.,Dalby, K.N.,Ghose, R.; ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin.; Proc.Natl.Acad.Sci.USA, 120:e2300902120-e2300902120, 2023; PubMed: 37068230; DOI: 10.1073/pnas.2300902120

実験手法

X-RAY DIFFRACTION (2.22 Å)