8FMF
Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (1 tetramer in the AU)
Summary for 8FMF
| Entry DOI | 10.2210/pdb8fmf/pdb |
| Descriptor | SAVED domain-containing protein, Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, GLYCEROL, ... (8 entities in total) |
| Functional Keywords | cyclic dinucleotide, bacterial immunity, cbass, cap5 effector dna endonuclease, viral defense, immune system |
| Biological source | Pseudomonas syringae |
| Total number of polymer chains | 4 |
| Total formula weight | 175537.94 |
| Authors | Rechkoblit, O.,Kreitler, D.F.,Aggarwal, A.K. (deposition date: 2022-12-23, release date: 2024-02-07, Last modification date: 2024-05-29) |
| Primary citation | Rechkoblit, O.,Sciaky, D.,Kreitler, D.F.,Buku, A.,Kottur, J.,Aggarwal, A.K. Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides. Nat.Struct.Mol.Biol., 31:767-776, 2024 Cited by PubMed: 38321146DOI: 10.1038/s41594-024-01220-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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