8FMF

Structure of CBASS Cap5 from Pseudomonas syringae as an activated tetramer with the cyclic dinucleotide 3'2'-c-diAMP ligand (1 tetramer in the AU)

8FMF の概要

• エントリーDOI: 10.2210/pdb8fmf/pdb
• 分子名称: SAVED domain-containing protein, Cyclic (adenosine-(2'-5')-monophosphate-adenosine-(3'-5')-monophosphate, GLYCEROL, ... (8 entities in total)
• 機能のキーワード: cyclic dinucleotide, bacterial immunity, cbass, cap5 effector dna endonuclease, viral defense, immune system
• 由来する生物種: Pseudomonas syringae
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 175537.94

構造登録者

Rechkoblit, O.,Kreitler, D.F.,Aggarwal, A.K. (登録日: 2022-12-23, 公開日: 2024-02-07, 最終更新日: 2024-05-29)

• 主引用文献: Rechkoblit, O.,Sciaky, D.,Kreitler, D.F.,Buku, A.,Kottur, J.,Aggarwal, A.K.; Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides.; Nat.Struct.Mol.Biol., 31:767-776, 2024; PubMed: 38321146; DOI: 10.1038/s41594-024-01220-x

実験手法

X-RAY DIFFRACTION (2.1 Å)