8FKC

Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33544

8FKC の概要

• エントリーDOI: 10.2210/pdb8fkc/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-N-(5-cyanopyridin-3-yl)-5-nitrobenzamide, ... (5 entities in total)
• 機能のキーワード: nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34380.14

構造登録者

MacTavish, B.S.,Kojetin, D.J. (登録日: 2022-12-21, 公開日: 2024-04-17)

• 主引用文献: MacTavish, B.S.,Kojetin, D.J.; Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and SR33544; To Be Published,

実験手法

X-RAY DIFFRACTION (1.42 Å)