8FJO

X-ray crystal structure of CYP124A1 from Mycobacterium Marinum in complex with farnesyl acetate

Summary for 8FJO

Entry DOI	10.2210/pdb8fjo/pdb
Descriptor	Cytochrome P450 124A1, Cyp124A1, PROTOPORPHYRIN IX CONTAINING FE, (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl acetate, ... (8 entities in total)
Functional Keywords	substrate bound, oxidoreductase, oxidoreductase-substrate complex, oxidoreductase/substrate
Biological source	Mycobacterium marinum
Total number of polymer chains	1
Total formula weight	51033.23
Authors	Ghith, A.,Bruning, J.B.,Bell, S.G. (deposition date: 2022-12-20, release date: 2023-03-29, Last modification date: 2024-05-22)
Primary citation	Ghith, A.,Bruning, J.B.,Bell, S.G. The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 737:109554-109554, 2023 Cited by PubMed: 36842492 DOI: 10.1016/j.abb.2023.109554 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation