8FJN
Crystal Structure of the Trypanosoma brucei DOT1A histone H3K76 methyltransferase in complex with AdoHcy - C2221 space group
Summary for 8FJN
Entry DOI | 10.2210/pdb8fjn/pdb |
Related | 8FJM |
Descriptor | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (6 entities in total) |
Functional Keywords | histone lysine methyltransferase, histone-modifying enzyme, dot1a, trypanosoma brucei, adohcy complex, transferase |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 1 |
Total formula weight | 29851.11 |
Authors | |
Primary citation | Frisbie, V.S.,Hashimoto, H.,Xie, Y.,Baeza, J.,Nguyen, T.,Yuan, Z.,Garcia, B.A.,Debler, E.W. Structure and Mechanism of the atypical Trypanosoma brucei DOT1A histone H3K76 methyltransferase To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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