8FHH

Wildtype rabbit TRPV5 in nanodiscs in the presence of oleoyl coenzyme A, Closed stated

8FHH の概要

• エントリーDOI: 10.2210/pdb8fhh/pdb
• EMDBエントリー: 29085
• 分子名称: Transient receptor potential cation channel subfamily V member 5, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL (3 entities in total)
• 機能のキーワード: trpv5, trp channel, oleoyl coenzyme a, closed state, membrane protein
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 341351.83

構造登録者

De Jesus-Perez, J.J.,Moiseenkova-Bell, V.Y. (登録日: 2022-12-14, 公開日: 2023-11-01)

• 主引用文献: Lee, B.H.,De Jesus Perez, J.J.,Moiseenkova-Bell, V.,Rohacs, T.; Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.; Nat Commun, 14:5883-5883, 2023; PubMed: 37735536; DOI: 10.1038/s41467-023-41577-z

実験手法

ELECTRON MICROSCOPY (3.09 Å)