8FHE

Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662

Summary for 8FHE

• Entry DOI: 10.2210/pdb8fhe/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, Nuclear receptor corepressor 1, 2-chloro-5-nitro-N-phenylbenzamide, ... (4 entities in total)
• Functional Keywords: nuclear receptors, tzds, drug design, therapeutic targets, transcription, transcription-agonist complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 34235.02

Authors

Shang, J.,Kojetin, D.J. (deposition date: 2022-12-14, release date: 2024-03-20, Last modification date: 2024-10-23)

• Primary citation: Shang, J.,Kojetin, D.J.; Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and GW9662; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)