8FH1
Crystal structure of mutant Androgen Receptor ligand binding domain F877L/T878A with DHT
Summary for 8FH1
Entry DOI | 10.2210/pdb8fh1/pdb |
Descriptor | Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ar, androgen receptor, dht, steroid receptor, gene regulation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 30416.63 |
Authors | Doamekpor, S.K.,Tong, L. (deposition date: 2022-12-13, release date: 2023-04-12, Last modification date: 2024-05-22) |
Primary citation | Doamekpor, S.K.,Peng, P.,Xu, R.,Ma, L.,Tong, Y.,Tong, L. A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations. Acta Crystallogr.,Sect.F, 79:95-104, 2023 Cited by PubMed: 36995121DOI: 10.1107/S2053230X23002224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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