8FF2
Amyloid-beta (1-40) fibrils derived from a CAA patient
Summary for 8FF2
| Entry DOI | 10.2210/pdb8ff2/pdb |
| EMDB information | 29036 29037 29038 |
| Descriptor | Amyloid-beta precursor protein (1 entity in total) |
| Functional Keywords | amyloid, vascular, fibril, human, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 10 |
| Total formula weight | 43358.52 |
| Authors | Crooks, E.J.,Fu, Z.,Chowdhury, S.,Smith, S.O. (deposition date: 2022-12-07, release date: 2023-12-06, Last modification date: 2024-05-01) |
| Primary citation | Fu, Z.,Crooks, E.J.,Irizarry, B.A.,Zhu, X.,Chowdhury, S.,Van Nostrand, W.E.,Smith, S.O. An electrostatic cluster guides A beta 40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy. J.Struct.Biol., 216:108092-108092, 2024 Cited by PubMed: 38615725DOI: 10.1016/j.jsb.2024.108092 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.87 Å) |
Structure validation
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