8FD0

Crystal structure of bovine rod opsin in complex with a nanobody

8FD0 の概要

• エントリーDOI: 10.2210/pdb8fd0/pdb
• 分子名称: Rhodopsin, Nanobody Nb2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: transmembrane protein, gpcr, nanobody, membrane protein
• 由来する生物種: Lama glama (llama); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 108797.56

構造登録者

Salom, D.,Palczewski, K.,Kiser, P.D. (登録日: 2022-12-01, 公開日: 2023-08-30, 最終更新日: 2023-09-20)

• 主引用文献: Wu, A.,Salom, D.,Hong, J.D.,Tworak, A.,Watanabe, K.,Pardon, E.,Steyaert, J.,Kandori, H.,Katayama, K.,Kiser, P.D.,Palczewski, K.; Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.; Nat Commun, 14:5209-5209, 2023; PubMed: 37626045; DOI: 10.1038/s41467-023-40911-9

実験手法

X-RAY DIFFRACTION (3.71 Å)