8FBN
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
Summary for 8FBN
Entry DOI | 10.2210/pdb8fbn/pdb |
Descriptor | KWOCA_73 (1 entity in total) |
Functional Keywords | designed protein, protein assemblies, negative design, cryptic transmembrane domains, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 6 |
Total formula weight | 145938.53 |
Authors | Wang, J.Y.,Khmelinskaia, A.,Bera, A.K.,King, N.P. (deposition date: 2022-11-29, release date: 2023-03-22, Last modification date: 2024-05-22) |
Primary citation | Wang, J.Y.J.,Khmelinskaia, A.,Sheffler, W.,Miranda, M.C.,Antanasijevic, A.,Borst, A.J.,Torres, S.V.,Shu, C.,Hsia, Y.,Nattermann, U.,Ellis, D.,Walkey, C.,Ahlrichs, M.,Chan, S.,Kang, A.,Nguyen, H.,Sydeman, C.,Sankaran, B.,Wu, M.,Bera, A.K.,Carter, L.,Fiala, B.,Murphy, M.,Baker, D.,Ward, A.B.,King, N.P. Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120:e2214556120-e2214556120, 2023 Cited by PubMed: 36888664DOI: 10.1073/pnas.2214556120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.04 Å) |
Structure validation
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