8FB8

Crystal structure of Ky15.10-Y100EK Fab in complex with circumsporozoite protein KQPA peptide

8FB8 の概要

• エントリーDOI: 10.2210/pdb8fb8/pdb
• 分子名称: Ky15.10-YK Antibody, heavy chain, Ky15.10-YK Antibody, light chain, Circumsporozoite protein KQPA peptide, ... (5 entities in total)
• 機能のキーワード: malaria, antibody, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50149.67

構造登録者

Kang, R.W.,Thai, E.,Julien, J.P. (登録日: 2022-11-29, 公開日: 2023-11-01, 最終更新日: 2024-03-20)

• 主引用文献: Thai, E.,Murugan, R.,Binter, S.,Burn Aschner, C.,Prieto, K.,Kassardjian, A.,Obraztsova, A.S.,Kang, R.W.,Flores-Garcia, Y.,Mathis-Torres, S.,Li, K.,Horn, G.Q.,Huntwork, R.H.C.,Bolscher, J.M.,de Bruijni, M.H.C.,Sauerwein, R.,Dennison, S.M.,Tomaras, G.D.,Zavala, F.,Kellam, P.,Wardemann, H.,Julien, J.P.; Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.; Cell Rep, 42:113330-113330, 2023; PubMed: 38007690; DOI: 10.1016/j.celrep.2023.113330

実験手法

X-RAY DIFFRACTION (1.69 Å)