8FAT
Crystal structure of Ky224 Fab in complex with circumsporozoite protein NPDP peptide
Summary for 8FAT
Entry DOI | 10.2210/pdb8fat/pdb |
Descriptor | Ky224 Antibody, heavy chain, Ky224 Antibody, light chain, Circumsporozoite protein NPDP peptide (3 entities in total) |
Functional Keywords | malaria, antibody, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 98139.67 |
Authors | Kassardjian, A.,Thai, E.,Julien, J.P. (deposition date: 2022-11-28, release date: 2023-11-01, Last modification date: 2024-03-20) |
Primary citation | Thai, E.,Murugan, R.,Binter, S.,Burn Aschner, C.,Prieto, K.,Kassardjian, A.,Obraztsova, A.S.,Kang, R.W.,Flores-Garcia, Y.,Mathis-Torres, S.,Li, K.,Horn, G.Q.,Huntwork, R.H.C.,Bolscher, J.M.,de Bruijni, M.H.C.,Sauerwein, R.,Dennison, S.M.,Tomaras, G.D.,Zavala, F.,Kellam, P.,Wardemann, H.,Julien, J.P. Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42:113330-113330, 2023 Cited by PubMed: 38007690DOI: 10.1016/j.celrep.2023.113330 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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