8FAS

Crystal structure of Ky230 Fab in complex with circumsporozoite protein NANP5 peptide

Summary for 8FAS

Entry DOI	10.2210/pdb8fas/pdb
Descriptor	Ky230 Antibody, heavy chain, Ky230 Antibody, light chain, Circumsporozoite protein NANP5 peptide, ... (5 entities in total)
Functional Keywords	malaria, antibody, immune system
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	3
Total formula weight	50399.99
Authors	Kassardjian, A.,Thai, E.,Julien, J.P. (deposition date: 2022-11-28, release date: 2023-11-01, Last modification date: 2024-03-20)
Primary citation	Thai, E.,Murugan, R.,Binter, S.,Burn Aschner, C.,Prieto, K.,Kassardjian, A.,Obraztsova, A.S.,Kang, R.W.,Flores-Garcia, Y.,Mathis-Torres, S.,Li, K.,Horn, G.Q.,Huntwork, R.H.C.,Bolscher, J.M.,de Bruijni, M.H.C.,Sauerwein, R.,Dennison, S.M.,Tomaras, G.D.,Zavala, F.,Kellam, P.,Wardemann, H.,Julien, J.P. Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Rep, 42:113330-113330, 2023 Cited by PubMed: 38007690 DOI: 10.1016/j.celrep.2023.113330 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation