8F8Z

PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide

8F8Z の概要

• エントリーDOI: 10.2210/pdb8f8z/pdb
• 分子名称: Lysine-specific demethylase PHF2, H3 N-Terminal Peptide, ZINC ION, ... (6 entities in total)
• 機能のキーワード: methyl-lysine binding; aromatic cage; plant homeodomain (phd); jumonji domain; plant homeodomain finger 2 (phf2); histone h3 lysine 4 tri-methylation (h3k4me3), oxidoreductase-transferase complex, oxidoreductase/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 111043.76

構造登録者

Horton, J.R.,Cheng, X. (登録日: 2022-11-22, 公開日: 2023-01-18, 最終更新日: 2023-02-08)

• 主引用文献: Horton, J.R.,Zhou, J.,Chen, Q.,Zhang, X.,Bedford, M.T.,Cheng, X.; A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.; J.Biol.Chem., 299:102862-102862, 2022; PubMed: 36596360; DOI: 10.1016/j.jbc.2022.102862

実験手法

X-RAY DIFFRACTION (3.3 Å)