8F8E

Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound

8F8E の概要

• エントリーDOI: 10.2210/pdb8f8e/pdb
• 分子名称: DDB1- and CUL4-associated factor 1, (3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide, CITRIC ACID, ... (4 entities in total)
• 機能のキーワード: wd-repeat, wdr, dcaf1, sgc, transferase, structural genomics, structural genomics consortium, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72256.50

構造登録者

Kimani, S.,Li, A.,Dong, A.,Li, Y.,Hutchinson, A.,Seitova, A.,Wilson, B.,Al-Awar, R.,Vedadi, M.,Brown, P.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (登録日: 2022-11-21, 公開日: 2023-03-01, 最終更新日: 2024-05-22)

• 主引用文献: Kimani, S.,Li, A.,Dong, A.,Li, Y.,Hutchinson, A.,Seitova, A.,Wilson, B.,Al-Awar, R.,Vedadi, M.,Brown, P.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound; To be published,

実験手法

X-RAY DIFFRACTION (1.55 Å)