8F85
Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM851
8F85 の概要
エントリーDOI | 10.2210/pdb8f85/pdb |
分子名称 | Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{2-[3-({(6M)-2,4-diamino-6-[2-(trifluoromethyl)phenyl]pyrimidin-5-yl}oxy)propoxy]phenyl}propanoic acid, ... (4 entities in total) |
機能のキーワード | ssgcid, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
由来する生物種 | Mycobacterium ulcerans |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 20255.47 |
構造登録者 | Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2022-11-21, 公開日: 2023-12-13, 最終更新日: 2024-06-19) |
主引用文献 | Lovell, S.,Battaile, K.P.,Staker, B.L. Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM851 To be published, |
実験手法 | X-RAY DIFFRACTION (1.15 Å) |
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