8F7U

Macrocyclic Plasmin Inhibitor

Summary for 8F7U

• Entry DOI: 10.2210/pdb8f7u/pdb
• Related: 7T52
• Descriptor: Activation peptide, (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide, SULFATE ION, ... (5 entities in total)
• Functional Keywords: protease, inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 56869.15

Authors

Guojie, W. (deposition date: 2022-11-20, release date: 2023-02-08)

• Primary citation: Guojie, W.; Synthesis and structural characterization of new macrocyclicplasmin inhibitors; Chemmedchem, 2023

Experimental method

X-RAY DIFFRACTION (1.47 Å)