8F5W

Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Dihydrothymine and NADPH Quasi-Anaerobically

8F5W の概要

• エントリーDOI: 10.2210/pdb8f5w/pdb
• 分子名称: Dihydropyrimidine dehydrogenase [NADP(+)], IRON/SULFUR CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: dihydropyrimidine dehydrogenase, protein, mutant, dihyrdothymine, nadph, flavoprotein
• 由来する生物種: Sus scrofa (pig)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 460429.08

構造登録者

Kaley, N.,Smith, M.,Forouzesh, D.,Liu, D.,Moran, G. (登録日: 2022-11-15, 公開日: 2023-02-01, 最終更新日: 2023-10-25)

• 主引用文献: Smith, M.M.,Forouzesh, D.C.,Kaley, N.E.,Liu, D.,Moran, G.R.; Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes.; Arch.Biochem.Biophys., 736:109517-109517, 2023; PubMed: 36681231; DOI: 10.1016/j.abb.2023.109517

実験手法

X-RAY DIFFRACTION (1.97 Å)