8F3U

Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant penicillin bound form from Enterococcus faecium

Summary for 8F3U

• Entry DOI: 10.2210/pdb8f3u/pdb
• Related: 8F3F
• Descriptor: Penicillin binding protein 5, OPEN FORM - PENICILLIN G, SULFATE ION, ... (4 entities in total)
• Functional Keywords: penicillin binding, antibiotic resistance, antibiotics, antibiotic
• Biological source: Enterococcus faecium
• Total number of polymer chains: 1
• Total formula weight: 72541.89

Authors

D'Andrea, E.D.,Choy, M.S.,Schoenle, M.V.,Page, R.,Peti, W. (deposition date: 2022-11-10, release date: 2023-07-05, Last modification date: 2024-03-13)

• Primary citation: Hunashal, Y.,Kumar, G.S.,Choy, M.S.,Da Silva Santiago, A.,D'Andrea, E.D.,Schoenle, M.V.,Arthur, M.,Rice, L.B.,Page, R.,Peti, W.; The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics; Nat Commun, 2023

Experimental method

X-RAY DIFFRACTION (2.6 Å)