8F3G
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant in the penicillin bound form from Enterococcus faecium
Summary for 8F3G
Entry DOI | 10.2210/pdb8f3g/pdb |
Related | 8F3F |
Descriptor | Penicillin binding protein 5, OPEN FORM - PENICILLIN G, SULFATE ION, ... (4 entities in total) |
Functional Keywords | penicillin binding, antibiotic resistance, antibiotic |
Biological source | Enterococcus faecium |
Total number of polymer chains | 1 |
Total formula weight | 72884.10 |
Authors | D'Andrea, E.D.,Choy, M.S.,Schoenle, M.V.,Page, R.,Peti, W. (deposition date: 2022-11-10, release date: 2023-07-05, Last modification date: 2024-03-13) |
Primary citation | Hunashal, Y.,Kumar, G.S.,Choy, M.S.,Da Silva Santiago, A.,D'Andrea, E.D.,Schoenle, M.V.,Arthur, M.,Rice, L.B.,Page, R.,Peti, W. The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023 |
Experimental method | X-RAY DIFFRACTION (3.59 Å) |
Structure validation
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