8F1Y

EGFR kinase in complex with poziotinib

Summary for 8F1Y

• Entry DOI: 10.2210/pdb8f1y/pdb
• Descriptor: Epidermal growth factor receptor, 1-[4-[4-[[3,4-bis(chloranyl)-2-fluoranyl-phenyl]amino]-7-methoxy-quinazolin-6-yl]oxypiperidin-1-yl]propan-1-one, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: egfr, kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38321.92

Authors

Beyett, T.S.,Eck, M.J. (deposition date: 2022-11-06, release date: 2023-11-08)

• Primary citation: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with poziotinib; To be published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)