8F1X

EGFR kinase in complex with mobocertinib (TAK-788)

Summary for 8F1X

• Entry DOI: 10.2210/pdb8f1x/pdb
• Descriptor: Epidermal growth factor receptor, propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate (3 entities in total)
• Functional Keywords: egfr, kinase, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38224.15

Authors

Beyett, T.S.,Eck, M.J. (deposition date: 2022-11-06, release date: 2023-11-08)

• Primary citation: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with mobocertinib (TAK-788); To be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)