8F1H

EGFR kinase in complex with TAS6417 (CLN-081)

Summary for 8F1H

• Entry DOI: 10.2210/pdb8f1h/pdb
• Descriptor: Epidermal growth factor receptor, N-[(5P,8S,10R)-4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: egfr, kinase, exon 20, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38225.01

Authors

Beyett, T.S.,Eck, M.J. (deposition date: 2022-11-05, release date: 2023-11-08)

• Primary citation: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with TAS6417 (CLN-081); To be published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)