8F1H

EGFR kinase in complex with TAS6417 (CLN-081)

8F1H の概要

• エントリーDOI: 10.2210/pdb8f1h/pdb
• 分子名称: Epidermal growth factor receptor, N-[(5P,8S,10R)-4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide, CITRIC ACID, ... (4 entities in total)
• 機能のキーワード: egfr, kinase, exon 20, inhibitor, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38225.01

構造登録者

Beyett, T.S.,Eck, M.J. (登録日: 2022-11-05, 公開日: 2023-11-08)

• 主引用文献: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with TAS6417 (CLN-081); To be published,

実験手法

X-RAY DIFFRACTION (2.8 Å)