8F1C
Voltage-gated potassium channel Kv3.1 with novel positive modulator (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one (compound 4)
8F1C の概要
エントリーDOI | 10.2210/pdb8f1c/pdb |
EMDBエントリー | 28793 28795 |
分子名称 | Potassium voltage-gated channel subfamily C member 1, ZINC ION, (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one, ... (5 entities in total) |
機能のキーワード | ion channel, positive modulator, voltage gated, voltage gated potassium channel, transport protein |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 256190.91 |
構造登録者 | |
主引用文献 | Chen, Y.T.,Hong, M.R.,Zhang, X.J.,Kostas, J.,Li, Y.,Kraus, R.L.,Santarelli, V.P.,Wang, D.,Gomez-Llorente, Y.,Brooun, A.,Strickland, C.,Soisson, S.M.,Klein, D.J.,Ginnetti, A.T.,Marino, M.J.,Stachel, S.J.,Ishchenko, A. Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc.Natl.Acad.Sci.USA, 120:e2220029120-e2220029120, 2023 Cited by PubMed: 37812700DOI: 10.1073/pnas.2220029120 主引用文献が同じPDBエントリー |
実験手法 | ELECTRON MICROSCOPY (2.92 Å) |
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